Buy Nexletol  (bempedoic acid)

What is Nexletol (bempedoic acid) for?

Buy Nexletol  (bempedoic acid). (Nexletol bempedoic acid is a drug that helps lower high blood cholesterol levels. It is used for:

• heterozygous familial hypercholesterolemia
• established atherosclerotic cardiovascular disease

It is taken along with diet and the highest statin therapy.

It comes in a capsule form with 180 mg bempedoic acid.

How does Nexletol (bempedoic acid) work?

Bempedoic acid works by blocking an enzyme in the liver. This enzyme is responsible for making cholesterol. By doing this, it lowers blood cholesterol levels, including LDL-cholesterol.

Statins work differently by blocking another enzyme. Even with the highest statin dosage, some patients still can’t get their LDL-C levels low enough.

Where has Nexletol (bempedoic acid) been approved?

Nexletol (bempedoic acid) has been approved by:

• The Food and Drug Administration (FDA), USA, on February 21, 2020, for treating high cholesterol with diet and statins.
• The European Medicines Agency (EMA), Europe, on April 1, 2020, under the brand name Nilemdo for treating high cholesterol and mixed dyslipidemia. It is used with diet and statins, with or without other medicines.

Nexletol is the first oral, once-daily, non-statin LDL-C lowering medicine approved since 2002 for indicated patients.

Please note that this medicine may have also been approved in other regions than the ones we’ve listed. If you have a question about its approval in a specific country feel free to contact our support team.

How is Nexletol (bempedoic acid) taken?

The standard dosage is:

• One 180 mg capsule per day, taken with or without food.

Complete information about Nexletol (bempedoic acid) dosage and administration can be found in the official prescribing information listed in our references section.

Note: Please consult with your treating doctor for personalised dosing.

Are there any known adverse reactions or side effects of Nexletol (bempedoic acid)?

Common adverse reactions

The most common side effects (≥20% of patients) listed in the prescribing information include:

• Pain in your back, shoulder, legs, or arms
• Muscle spasm
• Stomach pain
• Anemia
• Abnormal liver function tests
• Wheezing, cough, chest congestion
• Cold symptoms such as stuffy nose, sneezing, sore throat.

Serious adverse reactions

The serious adverse reactions listed in the prescribing information include:

• • Increased levels of uric acid in your blood (hyperuricemia)
  • Tendon rupture or injury

Use in a specific population

Nexletol (bempedoic acid) can harm a fetus if a pregnant woman takes it. It’s best to avoid pregnancy and breastfeeding.

For a comprehensive list of side effects and adverse reactions please refer to the official prescribing information.

References

1. Full prescribing information [FDA]: Nexletol (bempedoic acid) [PDF]
Esperion, Feb 21, 2020

2. Nilemdo (bempedoic acid)
EMA, Apr 1, 2020

3. Esperion Announces FDA Approval of NEXLETOL™ (bempedoic acid) Tablet, an Oral, Once-Daily, Non-Statin LDL-Cholesterol Lowering Medicine
Press release, Feb 21, 2020

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