Buy Orkambi (lumacaftor/ivacaftor). Orkambi (lumacaftor/ivacaftor) is a medicine for cystic fibrosis (CF). It has two parts: lumacaftor and ivacaftor. It helps people with a specific CF gene mutation. This is the first treatment for this mutation.
It’s for people 12 years old and up. For those 6 to 11, it’s a different dose.
Cystic Fibrosis (CF) makes mucus thick. This affects the lungs and digestive system. It leads to breathing and digestion problems, infections, and diabetes.
CF is caused by a gene mutation. This gene makes a protein that helps with mucus and digestive juices. The mutation makes these juices thick and sticky. Orkambi fixes this by boosting the protein’s function.
Orkambi (lumacaftor/ivacaftor)* is approved for CF treatment in several places:
This medicine might be approved in other places too. If you have questions, contact our support team.
Adults and teens over 12 take two tablets every 12 hours. Each tablet has 200 mg of lumacaftor and 125 mg of ivacaftor.
Kids 6 to 11 years old take two tablets every 12 hours. Each tablet has 100 mg of lumacaftor and 125 mg of ivacaftor.
People with liver problems or taking certain drugs should take less. Start with a lower dose if taking strong CYP3A inhibitors.
For more details, see the official prescribing information in our references section.
Note: Always talk to your doctor about the right dose for you.
The most common side effects include: