Buy Orladeyo (berotralstat)

What is Orladeyo (berotralstat)

Buy Orladeyo (berotralstat). Orladeyo (berotralstat) is a drug that stops hereditary angioedema (HAE) attacks. It works for adults and kids 12 and up.

It’s not for treating sudden HAE attacks. It’s only for preventing them.

It comes in capsules with 150 or 110 mg of berotralstat.

How does Orladeyo (berotralstat) work?

HAE is a rare disease that causes sudden swelling. It happens when there’s not enough C1 inhibitor protein. This leads to bradykinin activation, causing swelling.

Berotralstat stops plasma kallikrein from working. This helps prevent HAE attacks.

Where has Orladeyo (berotralstat) been approved?

Orladeyo (berotralstat) is approved for HAE prevention by:

• The Food and Drug Administration (FDA), USA on December 3, 2020.
• The Pharmaceuticals and Medical Devices Agency (PMDA), Japan on January 22, 2021.
• The European Medicines Agency (EMA) on April 30, 2021.

It’s the first oral, non-steroid drug for this use.

This medicine might be approved in other places too. If you’re unsure, contact our support team.

How is Orladeyo (berotralstat) taken?

The usual dose is:

• One 150 mg capsule taken orally once daily with food

For those with liver issues or on kidney dialysis, take one 110 mg capsule daily with food.

Warning: do not take more than one capsule of Orladeyo a day because extra doses can cause heart rhythm problems.

For full details on dosage and use, see the official prescribing information in our references section.

Note: Please consult with your treating doctor for personalised dosing.

Are there any known adverse reactions or side effects of Orladeyo (berotralstat)?

Common adverse reactions

The most common side effects (≥20% of patients) include:

• Belly (abdominal) pain
• Vomiting
• Diarrhea
• Back pain
• Heartburn

Serious adverse reactions

The serious side effects listed include:

• Heart rhythm problems (QT prolongation)

Use in a specific population

Orladeyo (berotralstat) can harm a fetus. It’s advised to avoid pregnancy and breastfeeding.

For a comprehensive list of side effects and adverse reactions please refer to the official prescribing information.

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